Bacteria Resistant to ALL Drugs Shows up in Denmark
Agricultural use of antibiotics is by far the greatest threat to us, promoting drug resistance on a grander scale than hospital use. We must get all countries to agree to eliminate colistin and carbapenem antibiotics, in particular, from animal use. They are our last ditch antibiotics at a time when there is little drug development. This, and limiting some types of food imports, will slow the tide of this latest superbug threatening us. Its arrival is inevitable though, given global travel and trade. We’ll just need to keep our finger in the dike for now while hoping that the government will restrict the importation of foods likely to be carriers of this gene, greatly reduce or bar the use of critical antibiotics in agriculture, and will allocate new resources to the development of treatments for these resistant organisms.
Continue reading New Superbug Resistant To All Antibiotics Linked To Imported Meat, forbes, DEC 10, 2015.
Statement by Antibiotic Resistance Action Center on spread of dangerous superbug gene from China to Denmark, publichealth, December 3, 2015.
Roche acquires GeneWEAVE to strengthen offerings in microbiology diagnostics
Roche has signed a definitive agreement under which it will acquire GeneWEAVE BioSciences, Inc. Roche has been buying the company focused on innovative, clinical microbiology diagnostics solutions, for up to $425 million. With the deal, Roche has further strengthened its commitment to fight superbugs.
Sources and more information
Roche acquires GeneWEAVE to strengthen offerings in microbiology diagnostics, geneweave news, August 13, 2015.
Roche buys ‘superbug’ diagnostics firm for up to $425 million, Reuters, Aug 13, 2015.
How antibiotics are being used to compensate for the overcrowded, stressful conditions on industrial farms and how that’s creating superbugs that threaten public health.
Lance Price is a public health researcher who works at the interface between science and policy to address the growing crisis of antibiotic resistance. In the laboratory, Dr. Price uses cutting-edge DNA sequencing to trace the origins of new antibiotic-resistant pathogens. By analyzing the genomes of bacteria found in humans, food, and livestock, Dr. Price and his colleagues have traced the origins of new superbugs to industrial livestock production. Dr. Price and his colleagues have also begun to broaden the scope of foodborne disease to include urinary tract infections caused by foodborne E. coli.In the policy arena, Dr. Price works with grassroots organizations, NGOs, and policymakers to develop science-based policies to curb antibiotic abuse in food-animal production and stem the emergence of new superbugs. Dr. Price’s work was selected by Discover Magazine as one of the top 100 science stories of 2012. His research has also been covered by top-tier media around the world, including the BBC, New York Times, Los Angeles Times, Chicago Tribune, Scientific American, Men’s Journal, and Fitness Magazine, among others.
Antibiotic resistance genes are passed from one bacterium to another
Antibiotic resistance occurs when bacteria that cause infection are not killed by the antibiotics taken to stop the infection. The bacteria survive and continue to multiply, causing more harm. Widespread use of antibiotics promotes the spread of antibiotic resistance. Smart use of antibiotics is the key to decreasing, or even reversing, the spread of resistance.
Sources and more information
Is Antibiotic Resistance Bacteria Being Overused in Our Food? guardianlv, December 23, 2013.
The Community for Open Antimicrobial Drug Discovery (CO-ADD) was set up by scientists at the University of Queensland in Brisbane, Australia, in response to the growing problem of antimicrobial resistance.
U.S. scientists have discovered a new class of antibiotics that can kill a wide range of dangerous, drug-resistant bacteria
Antibiotic resistance is spreading faster than the introduction of new compounds into clinical practice, causing a public health crisis. Most antibiotics were produced by screening soil microorganisms, but this limited resource of cultivable bacteria was overmined by the 1960s. Synthetic approaches to produce antibiotics have been unable to replace this platform. Uncultured bacteria make up approximately 99% of all species in external environments, and are an untapped source of new antibiotics. We developed several methods to grow uncultured organisms by cultivation in situ or by using specific growth factors. Here we report a new antibiotic that we term teixobactin, discovered in a screen of uncultured bacteria. Teixobactin inhibits cell wall synthesis by binding to a highly conserved motif of lipid II (precursor of peptidoglycan) and lipid III (precursor of cell wall teichoic acid). We did not obtain any mutants of Staphylococcus aureus or Mycobacterium tuberculosis resistant to teixobactin. The properties of this compound suggest a path towards developing antibiotics that are likely to avoid development of resistance.
When the meat industry routinely misuses and overuses antibiotics, it threatens public health when essential drugs no longer work to treat infections, making us all less safe
Did you know that superbugs — dangerous bacteria resistant to antibiotics — are spreading from farms and into our communities? When antibiotics are used day after day to raise animals, drug resistant bacteria flourish, making antibiotics less effective for people. Take a look at a day in the life of this pig to learn why this is happening on industrial farms around the country.
Chicks are “vaccinated” as soon as their eggs are laid and before they even hatch
Today, large-scale poultry production has precious little to do with green fields and ruddy-cheeked farmers. Every year, more than 40 billion chickens are slaughtered worldwide for meat, the vast majority of them intensively factory-farmed.
They are often also dosed up with antibiotics — a preventative measure that is easier and cheaper than dealing with individual illnesses at a later date. Now experts are warning that the overuse of antibiotics in poultry farms around the world is creating a generation of superbugs that are resistant to treatment by virtually every drug in the medical establishment’s armoury.
With up to 80 per cent of the raw chicken on sale in some countries carrying these resistant bacteria, they can be transferred to humans during the handling of infected meat or the eating of undercooked produce.