Use medicines wisely

Each year thousands of injuries and deaths are caused by improper medication use. Many of these injuries could have been prevented. Published on 16 Aug 2011, by USFoodandDrugAdmin.

  1. Ask Questions
  2. Keep a Medicine List
  3. Follow Directions
  4. Safely Store and Throw Out Medicines
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The Vaccinated Girls : Sick and Betrayed

Some young girls are suffering from serious new medical conditions after being vaccinated against HPV with Gardasil

2015 documentary highlighting questions surrounding the HPV vaccine and a large number of young women who appear to have been affected since receiving gardasil shots.

Watch the video HERE.

More information
  • HPV Vaccines: A Danish Documentary, activistpost, April 30, 2015.
  • Danish TV Exposes Gardasil – “De Vaccinerede Piger” (With English Subtitles), beforeitsnews, April 30 2015.
  • Mainstream Media Attacks Katie Couric for Publishing Truth on Gardasil Vaccine, vaccineimpact, May 14, 2015.

HPV vaccination: should boys be vaccinated too?

Estimating the benefits to men of offering HPV vaccination to boys

This post content is published by The BMJ, aiming to lead the debate on health, and to engage doctors, researchers and health professionals to improve outcomes for patients.

man-vaccinated
As richer countries consider vaccinating males, the focus for lower income countries should remain on cervical cancer prevention. Image of vaccination in man by Army Medicine.

Vaccination of girls against the human papillomavirus (HPV) has been implemented in most developed countries, driven by prevention of cervical cancer as a public health priority. Bivalent (Cervarix, GSK) and quadrivalent (Gardasil, Merck) vaccines protect against subsequent infection with oncogenic HPV16/18, and quadrivalent vaccine protects against HPV6/11, which cause anogenital warts. Although HPV vaccination effectively protects against external genital lesions and anal intraepithelial neoplasia in males, only a few jurisdictions have so far recommended universal vaccination of boys. These include Australia, Austria, two Canadian provinces, and the United States. In other countries, a cautious approach has been due, in part, to uncertainties around the population level impact and cost effectiveness of vaccination of boys.

In a linked article, Bogaards and colleagues estimated the benefits to men of offering HPV vaccination to boys. They used a dynamic simulation and a bayesian synthesis to integrate the evidence on HPV related cancers in men. The analysis takes account of indirect protection from female vaccination: heterosexual men will benefit from reduced HPV circulation in females, so if coverage in girls is high the incremental benefit of vaccinating boys is driven by prevention of the residual burden of anal cancer in men who have sex with men.

The findings reinforce those of prior analyses that found that adding boys to established vaccination programmes in girls becomes less cost effective as female coverage increases. The cost effectiveness of vaccination of boys also depends on other local issues, especially vaccine type and vaccine and administration costs. A threshold total cost per vaccinated boy for cost effectiveness can be identified at any level of coverage in girls: such analyses can provide policy makers with the maximum rational vaccine price appropriate to the local environment. If vaccine coverage in girls is lower, however, the most effective use of resources is likely to involve increasing coverage in girls, if feasible.

In some countries, vaccination of boys might not be cost effective, even at lower vaccine prices, due to higher administration costs. Recent developments towards reduced dose schedules could help. In 2013 the European Medical Agency recommended a two dose schedule for the bivalent vaccine in girls, in 2014 the United Kingdom switched to a two dose schedule, and the World Health Organization now recommends two doses for girls <15. Two dose schedules are the most cost effective option for girls provided protection lasts for ≥20 years and reduced dose schedules in boys are also likely to increase cost effectiveness if adequate efficacy is maintained.

Bogaards and colleagues highlight the importance of vaccination for prevention of anal cancer in men who have sex with men. In part due to uncertainties in natural history, the effectiveness of anal cancer screening is not established. Primary prevention with targeted vaccination of men who have sex with men is an attractive option and is potentially more cost effective than universal vaccination of boys. The US Advisory Committee on Immunization Practices already recommends vaccination of men who have sex with men up to the age of 26 years. Older men who have sex with men could also potentially benefit. The UK’s Joint Committee on Vaccination and Immunisation, as an interim position, recently stated that a programme to vaccinate men aged 16-40 who have sex with men with a quadrivalent vaccine should be considered, if cost effective. Lower coverage rates expected with targeted versus universal male vaccination are an important consideration, and the two approaches are not mutually exclusive.

Several other new developments should be factored in to future policy decisions. A recent study showed that the bivalent vaccine is effective in women aged ≥25 without a history of HPV disease. With a transition to primary HPV screening occurring in several countries, an interesting possibility to be evaluated involves “screen and vaccinate” strategies in older women—that is, offering HPV screening, followed by vaccination for HPV negative women with extended (or perhaps no) recall for this group. Secondly, a nonavalent vaccine (Gardasil9, Merck), which protects against an extra five HPV types, has recently been recommended for use in the US. In women, this will increase protection against cervical cancer in those who are fully vaccinated (from about 70% to about 90%) but as most HPV cancers in men are attributed to types included in current vaccines, tiered pricing structures for new generation vaccines based on differential incremental benefits (and thus differential cost effectiveness thresholds) in girls versus boys could be considered.

All these policy decisions must consider burden of disease, safety, effectiveness, acceptability, equity, and cost effectiveness. Although the focus in developed countries has now, appropriately, shifted to considering these issues for boys, men who have sex with men, and older women, broader efforts to prevent cervical cancer should remain the priority in low and middle income countries. Of the 610 000 cancers annually attributable to HPV worldwide, 87% are cancers of the cervix, and three quarters of these occur in countries with a low or medium human development index. Even if a substantial majority of young girls in such counties were vaccinated, hundreds of millions of older women would remain at risk—vaccination alone will not prevent an expected increase in cervical cancers in the next few decades, driven by population ageing. Here, the priority focus should be the development of integrated programmes for vaccinating young girls and screening older women. Based on experience in developed countries, this will also provide benefits for men through indirect vaccine protection.

Sources and more information: Who should be vaccinated against HPV? BMJ 2015;350:h2244, 12 May 2015.

2010: Sophie Bonnet enquête sur les nouveaux jackpots des laboratoires pharmaceutiques

Canal+ éclaire les relations étroites entre les compagnies pharmaceutiques, les médecins et les politiques

Du Viagra pour les femmes ou un traitement pour énervés du volant, les labos ne savent plus quoi inventer pour nous faire avaler la pilule. Sophie Bonnet enquête sur leurs techniques marketing, et ça fait mal.

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Is Bought documentary exposing the ugly truth behind Vaccines, GMO’s and Big Pharma?

Vaccines. GMOs. Big Pharma.
Three big, BIG, okay… HUGE topics in one film

The truth behind vaccines, big pharma and your food

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Did vaccinated Women increase their Susceptibility to other HPV Types?

Women Who Received HPV Vaccine May Need More Shots…

HPV-vaccination image.
HPV Vaccination in Sao Paulo Brazil March 2014. Image via PAHO/WHO.
  • there are more than 80 HPV types …
  • … if a woman is already infected with HPV, the HPV vaccine cannot eliminate this infection …
  • … vaccinated women are not guaranteed to prevent cervical cancer and/or not to be infected with HPV: women in the study who received the Gardasil vaccine were less likely to be infected with the four strains of the virus included in the vaccine: about 11 percent of vaccinated women were (still) infected with HPV 6, 11, 16 or 18, compared with nearly 20 percent of unvaccinated women…
  • … however, the women who received the vaccine were more likely to be infected with other high-risk HPV strains not included in the vaccine. About 61 percent of the women who received the vaccine were infected with another type of high-risk HPV, compared with 40 percent of women who did not receive the vaccine…

Read Women Who Received HPV Vaccine May Need Another Shot,
livescience, April 22, 2015
and Comparison of HPV prevalence between HPV-vaccinated and non-vaccinated young adult women (20-26 years) ,
American Association for Cancer Research, Apr 19, 2015.

New Gardasil 9 vaccine, now targeting nine strains of human papillomavirus HPV

The new HPV vaccine is said to be more effective

Merck-banner image
Merck has been working to discover and develop vaccines for more than a century.
Their new 9vHPV vaccine prevented infection and disease related to HPV-31, 33, 45, 52, and 58 in a susceptible population and generated an antibody response to HPV-6, 11, 16, and 18.

A new version of the regular Gardasil vaccine – called Gardasil 9 – that fights nine strains of human papillomavirus offers greater cancer protection for women than the earlier one – which the NHS offers to all girls aged 12 to 13 – that targets only four.

The results of Gardasil 9 clinical trial, which was funded by Merck, are published in the New England Journal of Medicine.

We still need to remember that the vaccine prevent infections due to HPV only ; researchers will have to track the vaccinated women for many more years to see whether the two vaccines ultimately prevents more cancers…

The new vaccine already caused more side effects, from mild to severe…

Sources and more information

  • A 9-Valent HPV Vaccine against Infection and Intraepithelial Neoplasia in Women, The New England Journal of Medicine 2015; 372:711-723 February 19, 2015DOI: 10.1056/NEJMoa1405044 Supported by Merck.
  • Vaccine that targets 9 strains of HPV boosts cancer protection, study says, latimes, February 18, 2015.
  • FDA approves Gardasil 9 for prevention of certain cancers caused by five additional types of HPV, FDA News Release, December 10, 2014.

 

Médicaments sous influence

Documentaire 2015 avec Bernard Dalbergue et Michele Rivasi

Ancien du laboratoire Merck, Bernard Dalbergue décide, en 2011, de quitter son poste et avec lui un milieu sclérosé par les pratiques controversées et les mensonges. Il révèle ici les scandales dont il a été témoin : comment les laboratoires s’emploient à maquiller certaines études médicales, abusent des instances internationales et mettent en péril la santé de millions de personnes à travers le monde. Cette enquête décrypte, entre autres, les conditions de mise sur le marché international de quelques redoutables médicaments, consommés en masse, et confronte la logique financière des laboratoires au combat de savants et de victimes.

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Michel Georget, auteur agrégé de biologie, parle du vaccin Gardasil

Grand Angle, la réalité derrière le mythe, 2014

Michel Georget, agrégé de biologie, auteur de livres sur les vaccinations, expose son point de vue sur le “cancer du col de l’utérus“, et du vaccin gardasil.

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Did you take the Gardasil Cervarix HPV Vaccine Survey?

Hormones Matter has been struck by the depth and breadth of adverse events experienced by young girls and women who have been given the HPV vaccines Gardasil or Cervarix

Lucine women logo
Hormones Matter has been struck by the depth and breadth of adverse events experienced by young girls and women who have been given the HPV vaccines Gardasil or Cervarix.

At Hormones Matter we have been struck by the depth and breadth of adverse events experienced by young girls and women who have been given the HPV vaccines Gardasil or Cervarix. Anecdotal evidence is great, but objective data are better. We must resolve this issue, our daughter’s lives depend upon it.

We need your help to gather the data to understand the real prevalence of side-effects, the range and severity of side-effects and who is most at risk for these complications. Please take this survey and share it with your friends, sisters, colleagues and anyone you know who has been given the HPV vaccine. We will need thousands of women to find the connections. That requires crowdsourcing and sharing amongst women.

The survey is anonymous.

Because of the age of some of the girls given the HPV vaccine and the severity of the adverse events that include death and severe disability, we allow parents, family members and/or friends to take the survey for the affected individual.

Finally, this is a long survey, approximately 30 minutes. We wish it were shorter, but both the depth of the information and the limitations of survey software combine to make this a longer than desired survey. Given that some girls and women are dying or suffering from life long adverse events, we felt it was more important to be thorough than short and incomplete.

We will be creating a second survey, over the coming months, to assess the adverse events in boys and men now being given the vaccine.

Thank you in advance for taking the survey.

Sources and more information