Epigenetics

- Cellular and molecular effects of developmental exposure to diethylstilbestrol: implications for other environmental estrogens – 1995
- DES (Diethylstilbestrol) May Suppress Gene Important To Normal Female Reproductive Tract Development – 1998
- Developmental exposure to diethylstilbestrol alters uterine gene expression that may be associated with uterine neoplasia later in life – 2008
- Diethylstilbestrol (DES)-stimulated hormonal toxicity is mediated by ERα alteration of target gene methylation patterns and epigenetic modifiers (DNMT3A, MBD2, and HDAC2) in the mouse seminal vesicle – 2013
- Diethylstilbestrol induces oxidative DNA damage, resulting in apoptosis of spermatogonial stem cells in vitro – 2017
- Early Life Adverse Environmental Exposures Increase the Risk of Uterine Fibroid Development: Role of Epigenetic Regulation – 2016
- Effects of Neonatal Diethylstilbestrol (DES) Exposure on Morphology and Growth Patterns of Endometrial Epithelial Cells in CD-1 Mice – 1999
- Effects of Low-Dose Diethylstilbestrol Exposure on DNA Methylation in Mouse Spermatocytes – 2015
- Epigenetic effects of endocrine-disrupting chemicals on female reproduction: an ovarian perspective 2010
- Epigenetic Transgenerational Actions of Endocrine Disruptors and Male Fertility – 2010
- Environmental factors, epigenetics, and developmental origin of reproductive disorders – 2016
- Environmental signaling: from environmental estrogens to endocrine-disrupting chemicals and beyond – 2016
- Hsp90 and environmental impacts on epigenetic states: a model for the trans-generational effects of diethylstibesterol on uterine development and cancer – 2005
- Hypermethylation of homeobox A10 by in utero diethylstilbestrol exposure: an epigenetic mechanism for altered developmental programming – 2009
- In utero exposure to diethylstilbestrol and blood DNA methylation in women ages 40-59 years from the sister study – 2015
- In utero exposure to diethylstilbestrol (DES) does not increase genomic instability in normal or neoplastic breast epithelium – 2006
- Neonatal exposure to diethylstilbestrol alters expression of DNA methyltransferases and methylation of genomic DNA in the mouse uterus – 2009
- Persistent Hypomethylation in the Promoter of Nucleosomal Binding Protein 1 (Nsbp1) Correlates with Overexpression of Nsbp1 in Mouse Uteri Neonatally Exposed to Diethylstilbestrol or Genistein – 2008
- Prenatal exposure of mice to diethylstilbestrol disrupts T-cell differentiation by regulating Fas/Fas ligand expression through estrogen receptor element and nuclear factor-κB motifs – 2012
- Roles of p63 in the diethylstilbestrol-induced cervicovaginal adenosis – 2003
- The orphan nuclear receptor small heterodimer partner mediates male infertility induced by diethylstilbestrol in mice – 2009
- The Role of Hox Genes in Female Reproductive Tract Development, Adult Function, and Fertility – 2015
DES Transgenerational Effects
- Adverse Effects of the Model environmental Estrogen DES are transmitted to subsequent Generations – 2006
- Adverse health effects in children of women exposed in utero to diethylstilbestrol (DES) – 2016
- Diethylstilbestrol, teratogenesis, and carcinogenesis: medical/legal implications of its long-term sequelae, including third generation effects – 1990.
- Findings in Female Offspring of Women exposed in Utero to DiEthylStilbestrol – 2002
- Follow-up Study of Male and Female Offspring of DES-exposed Mothers – 1977
- IntraUterine Exposure to DiEthylStilbestrol: long-Term Effects in Humans – 2000
- Long-Term Effects of Exposure to #DiEthylStilbestrol – 1988
- Medical Conditions among Adult Offspring prenatally exposed to DiEthylStilbestrol – 2013
- Pregnant DES Daughters and their Offspring – 2005
- Proceedings of the Summit on Environmental Challenges to Reproductive Health and Fertility: Executive Summary, Developmental Programming and Fetal Origins of Adult Disease, The DES Example – 2009
- The Effect of DiEthylStilbestrol DES on Male Offspring – 1982
More DES DiEthylStilbestrol Resources
- DES studies on cancers and screening.
- DES studies on epigenetics and transgenerational effects.
- DES studies on fertility and pregnancy.
- DES studies on gender identity and psychological health.
- DES studies on in-utero exposure to DES and side-effects.
- DES studies on the genital tract.
- Papers on DES lawsuits.
- DES videos and posts tagged DES, the DES-exposed, DES victims.