DiEthylStilbestrol Resources: Gestational DES-Exposure and Side-Effects

In-Utero Exposure to DES

NCBI PubMed DiEthylStilbestrol Resources: Fetal DES-Exposure and Side-Effects.

• 2017 Current perspective of diethylstilbestrol (DES) exposure in mothers and offspring.
• 2014 Diethylstilbestrol story.
• 2014 Outcome and follow-up of diethylstilbestrol (DES) exposed individuals
• 2013 Exposure to diethylstilbestrol during sensitive life stages: a legacy of heritable health effects.
• 2011 NIH Research on the Health Effects of Diethylstilbestrol
• 2005 The History of DES, Lessons to be learned.
• 2004 Diethylstilbestrol exposure.
• 2003 CDC DES Update, for you, your family, and your health care provider.
• 2002 DES exposure and the aging woman: mothers and daughters.
• 2001 Consequences of DiEthylStilbestrol during Pregnancy ; 50 Years later still a Significant Problem.
• 1988 Long-Term Effects of Exposure to DiEthylStilbestrol.
• 1987 The effects in the human of DiEthylStilbestrol (DES) use during pregnancy.
• 1980 DES Diethylstilbestrol, National Women’s Health Network, Resource Guide 6.

DES Side Effects

– Bones

• Alterations in Estrogen Levels during Development affects the Skeleton – 1996
• Alterations of maternal Estrogen Levels during Gestation affect the Skeleton of Female Offspring – 1995
• Effect of in utero exposure to diethylstilbestrol on lumbar and femoral bone, articular cartilage, and the intervertebral disc in male and female adult mice progeny with and without swimming exercise – 2012

– Endometriosis

• Early-life factors and endometriosis risk – 2015
• Effects of Prenatal Environmental Exposures on the Development of Endometriosis in Female Offspring – 2016
• In utero exposures and the incidence of endometriosis – 2004

– Menarche

• • • Age at menarche among diethylstilbestrol granddaughters – 1995
    • Menarche, menopause, years of menstruation, and the incidence of osteoporosis: the influence of prenatal exposure to diethylstilbestrol – 2014.
    • Preterm Birth, fetal Growth, Age at Menarche among Women exposed prenatally to DiEthylStilbestrol – 2011

– Menopause

• • • Age at natural Menopause in Women exposed to DiEthylStilbestrol in Utero – 2006
    • Effects on the Menstrual Cycle of in Utero Exposure to DiEthylStilbestrol – 1994
    • The association between in utero cigarette smoke exposure and age at menopause – 2008.
    • Prenatal diethylstilbestrol exposure and reproductive hormones in premenopausal women – 2015

– Obesity

• • • Developmental Exposure to Endocrine Disruptors and the Obesity Epidemic – 2007
    • Developmental exposure to estrogenic compounds and obesity – 2005
    • Endocrine Disruptors and Obesity – 2017
    • Environmental Estrogens and Obesity: the Developmental Exposed DES Animal Model – 2009
    • Perinatal exposure to environmental estrogens and the development of obesity – 2007
    • Prenatal diethylstilbestrol exposure and risk of obesity in adult women – 2015

– Various Studies

• • • A focus group study of DES daughters: implications for health care providers – 2000
    • Adverse Health Outcomes in Women exposed in Utero to DiEthylStilbestrol – 2011
    • Antenatal exposure to DES: lessons learned…future concerns – 2007
    • Autoimmune Disease Incidence among Women prenatally exposed to Diethylstilbestrol – 2010.
    • Birth defects in the sons and daughters of women who were exposed in utero to diethylstilbestrol (DES) – 2010
    • Correlation of Mother’s Recall of DiEthylStilbestrol History with obstetrical Records – 1990
    • Cytology of 575 young women with prenatal exposure to diethylstilbestrol – 1976
    • Design and preliminary observations of National Cooperative Diethylstilbestrol Adenosis (DESAD) Project, – 1978
    • Developmental exposure to diethylstilbestrol (DES) alters uterine response to estrogens in prepubescent mice: low versus high dose effects – 2004
    • DiEthylStilbestrol and other Sex Hormones during Pregnancy – 1981
    • Diethylstilbestrol in pregnancy: an update – 1982
    • Differential Effects of Bisphenol A and Diethylstilbestrol on Human, Rat and Mouse Fetal Leydig Cell Function – 2012
    • Effects of diethylstilbestrol exposure during gestation on both maternal and offspring behavior – 2015
    • Effects of Neonatal Diethylstilbestrol (DES) Exposure on Morphology and Growth Patterns of Endometrial Epithelial Cells in CD-1 Mice – 1999
    • Effects of prenatal exposure to diethylstilbestrol (DES) on hemispheric laterality and spatial ability in human males – 1992
    • Endocrine disrupting chemicals and disease susceptibility – 2011
    • Gestational exposure to diethylstilbestrol alters cardiac structure/function, protein expression and DNA methylation in adult male mice progeny – 2013
    • Health risks and effects of prenatal exposure to diethylstilbestrol – 1983
    • Human papillomavirus associated with vaginal intraepithelial neoplasia in women exposed to diethylstilbestrol in utero – 1987
    • Increased incidence of cervical and vaginal dysplasia in 3,980 diethylstilbestrol-exposed young women. Experience of the National Collaborative Diethylstilbestrol Adenosis Project – 1984
    • In utero exposure to DES. Evaluation and followup of 199 women – 1978
    • Mortality in Women given DiEthylStilbestrol during Pregnancy – 2006
    • Not just a cervical ectropion. Three case reports of diethylstilbestrol (DES) exposed women presenting with vaginal discharge and cervical ectropion – 1999
    • Physiological effects and mechanisms of action of endocrine disrupting chemicals that alter estrogen signaling – 2010
    • Prenatal diethylstilbestrol exposure and performance on college entrance examinations – 1992
    • Prenatal Diethylstilbestrol Exposure and Risk of Uterine Leiomyomata in the Nurses’ Health Study II – 2013
    • Secondary sex ratio among women exposed to diethylstilbestrol in utero – 2007.
    • The effects of diethylstilbestrol administration on rat kidney. Ultrastructural study – 2013
    • The National DES Education Program: effectiveness of the California Health Provider Intervention – 2002
    • The Role of the Estrogen Receptor in DiEthylStilbestrol Toxicity – 1985
    • Time to pregnancy and secondary sex ratio in men exposed prenatally to diethylstilbestrol – 2007.
    • Vaginal and cervical squamous cell dysplasia in women exposed to diethylstilbestrol in utero – 1978

More DES DiEthylStilbestrol Resources

• • DES studies on cancers and screening.
  • DES studies on epigenetics and transgenerational effects.
  • DES studies on fertility and pregnancy.
  • DES studies on gender identity and psychological health.
  • DES studies on in-utero exposure to DES and side-effects.
  • DES studies on the genital tract.
  • Papers on DES lawsuits.
  • DES videos and posts tagged DES, the DES-exposed, DES victims.